Brain Imaging and Genetics in Behavioral Research

Publications

Are bigger brains smarter?

Genetic Underpinnings of Risky Behavior Relate To Altered Neuroanatomy

Genetic Underpinnings of Risky Behavior Relate To Altered Neuroanatomy

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Using a larger dataset than all previous studies on the subject combined, we found a small but significant connection between brain size and cognitive performance


Publication in Psychological Science

Press Release

Genetic Underpinnings of Risky Behavior Relate To Altered Neuroanatomy

Genetic Underpinnings of Risky Behavior Relate To Altered Neuroanatomy

Genetic Underpinnings of Risky Behavior Relate To Altered Neuroanatomy

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We conducted the largest brain imaging study of risky behavior (in the drinking, smoking, driving, and sexual domains) to date, in a sample that is representative of the UK population (N=12,675). We identified robust negative associations between risky behavior and its associated genetic disposition (estimated using a polygenic risk score) and grey matter volumes of distinct brain regions, including the anterior insula, amygdala, putamen, hypothalamus, and dorsolateral prefrontal cortex (dlPFC)


Preprint on BioArxiv

Is alcohol bad for your brain?

Genetic Underpinnings of Risky Behavior Relate To Altered Neuroanatomy

Is alcohol bad for your brain?

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  In a study of 19,825 adults, we found that that greater alcohol consumption was associated with lower global gray and white matter volume, suggesting that even moderate alcohol consumption can have negative effects on brain health. 


Preprint on BioArxiv